Target Of Rapamycin
International science club in France
Tor de France meeting 5th edition
4-5 October 2027, in Nice
TOR de France Association
TOR de France (TdF) is a scientific association founded in 2024. Its mission is to advance research and promote the dissemination of knowledge on the TOR (Target of Rapamycin) signalling pathway, as well as the consequences of its alteration in disease.
To achieve its goals, the association :
- Organises the biennial TOR de France meeting
- Facilitates networking among researchers and clinicians
- Centralises information on TOR related events and publications
Through these activities, TdF contributes to building a dynamic and collaborative research environment at both national and international levels.
Learn more about the TdF association (link to about at the end of community).
Pub Highlights
Cancer
Synergistic role of TFEB/TFE3 and mTORC1 in kidney cystogenesis and tumorigenesis
Cell biology
A TBK1/ULK1 signalling axis couples lysosomal stress to TFEB activation
Autophagy
Phosphorylation of OTUB1 promotes autophagy initiation under starvation
Cell biology
mTORC1 drives cell-autonomous astrocyte reactivity in tuberous sclerosis
Immunology
The role of mTORC2/RICTOR in immune cells and inflammatory diseases
Immunology
mTORC1 Promotes SARS-CoV-2 Replication and Attenuates Type I Interferon Responses in the Alveolar Epithelium: A Computational and Experimental Study
Immunology
Sensory neuronal mTORC1 kinase signaling establishes neuroimmune memory that initiates allergic immunity
Neuroscience
Genome-wide CRISPRi screen in human iNeurons identifies novel negative mTOR regulator genes associated with focal cortical dysplasia
Development
A transient RNP compartment boosts translation and growth of mammalian oocytes
Cancer
NFS1 activates PI3K/AKT/mTOR signaling to upregulate GPX4 expression and enhance ferroptosis resistance in osteosarcoma.
Upcoming events
Autophagy in Health and Disease: From Mechanisms to Therapeutics
Feb 08–11, 2027 | Fairmont Banff Springs, Banff, AB, Canada
Focus: Autophagy, lysosomal signalling, mTORC1
GRC: Lysosomal Diseases
May 16-21, 2027 | Les Diablerets, Switzerland
Focus: Lysosomal biology, Rag GTPases, mTORC1–TFEB signalling
CSHL: Mechanisms of Metabolic Signaling
May 17-21, 2027 | Cold Spring Harbor, New York, USA
Focus: Nutrient sensing, metabolic regulation, TORC1 signalling
MENTOR school mTOR parthophysiology
June 7-11, 2027 | Madrid, Spain
Focus: parthophysiology
News & Views
TOR de France board
Svetlana Dokudovskaya
IGR, Villejuif, France
Mario Pende
Necker Institute, Paris, France
Stéphanie Baulac
ICM, Paris, France
CommunicaTORs
Alisa Kirkin
University of Fribourg, Switzerland
Lucas Van Endert
ICM, Paris, France