TOR de France 2023
Memories of the 3rd edition
TOR de France 2023
5-6 October in Nice
Conferences - Program
Thursday - October 5th
NEUROBIOLOGY OF mTOR AND NEUROLOGICAL DISEASES
14:15 – Ghayda Mirzaa - Analysis of MTOR-related disorders through deep genomic and functional models reveals new clinical insights and distinct molecular pathomechanisms
15:00 – Jacek Jaworski - TBC1d5, novel mTORC1 substrate needed for neuronal development
15:15 – Deepika Mokkachamy Chellapandi - Identification of Dysregulated Molecular Pathways in Frataxin deficient Proprioceptive Neurons
15:25 – Angeliki Louvi - Human iPSC-derived cerebral organoids implicate mTOR pathway dysregulation in lissencephaly
15:40 – Stéphanie Baulac - Brain mosaicism in Epilepsy
15:55 – Amanda Almacellas Barbanoj - Gene Therapy for Epilepsy Associated with Focal Cortical Dysplasia type II
16:10 – Coffee Break
16:40 – Michele Studer - Modeling an emerging neurodevelopmental disorder affecting cortical gyrification
17:10 – Alice Gilbert - Mtor mouse models to dissect mechanisms in cortical malformations and epilepsy
17:25 – Jan Kudlacek - Neurons carrying mutated mTOR have a causal role in ictogenesis in focal cortical dysplasia
17:35 – Steffen Syrbe - De novo loss- and gain-of-function variants in RHEB cause a spectrum of neurodevelopmental disorders
17:45 – Francesco Avanzi - S6 Kinase is involved in TSC-related epilepsy through the regulation of TREK-1 potassium channel
17:55 – Daniela Cota - Role of microglial mTOR in obesity
18:30 – Poster session
Friday - October 6th
mTOR AND GROWTH CONTROL IN HEALTH AND DISEASE
09:30 – Kathrin Thedieck - New metabolic signals to mTOR: how cancer cells deal with tryptophan stress
10:15 – Zhenrui Pan - Function of GATOR1 complex in cisplatin resistance
10:25 – Jette Lengefeld - Cellular enlargement - A new hallmark of aging?
11:00 – Coffee Break
11:30 – Guillaume Canaud - Drug repositioning for rare diseases involving RAS/PIK3CA pathway
12:00 – Milica Vucetic - ER-storage response to protein misfolding activates ER-phagy via Fam134b transcriptional induction
12:10 – Marianna Maddaluno - Phosphoproteomics identifies RNA-metabolism defects in the brain in TSC
12:20 – Khaled Tighanimine - Metabolic adaptations of senescent cells
12:30 – Xiaolin Zi - The Potent Anti-Tumor Effects of Rhodiola Drinking Are Associated with the Inhibition of the mTOR Pathway and Modification of Tumor Metabolism
12:40 – Nitzan Samra - Neuronal cell growth and tissue size regulation by mTOR UTRs
12:55 – Sophia Ladraa -
13:05 – Lunch
MOLECULAR MECHANISMS OF MTOR REGULATION
14:15 – Robbie Loewith - TOR HD – revealing TOR regulation through cryoEM
15:00 – Iain Hay - The role of membrane binding in mTOR complex 2 signalling
15:10 – Constantinos Demetriades - Spatially and Functionally Distinct mTORC1 Entities Orchestrate the Cellular Response to Amino Acid Availability
15:25 – Aurelio Teleman - mTORC1 activity and tissue growth in vivo
16:30 – Jenna Jewell - inhibition of phosphodiesterase 4D suppresses mTORC1 signaling and pancreatic cancer growth
17:00 – Anders Mutvei - Prolonged deprivation of arginine or leucine induces PI3K/Akt-dependent reactivation of mTORC1
17:15 – Aishwarya Acharya - mTORC1 activity licenses its release from lysosomes
17:25 – Sarah Courbier - The role of TOR in the regulation of growth and defense responses in plants
17:40 – Mikhail Schepetilnikov - Selective Ribophagy in Plants: Unraveling the Mechanism of TOR-Driven Ribosome Degradation
17:50 – Fried Zwartkruis - mTORC1 restricts TFE3 activity by auto-regulating its presence on lysosomes
18:05 – Gennaro Napolitano - Selective modulation of mTORC1 signaling at the lysosome.
Some Memories
2023 Partners
