TOR de France 2023
Memories of the 4th edition
TOR de France 2025
9-10 October in Nice
Conferences - Program
Thursday - October 9th
9:30 – Arrival & Registration
10:30 – Welcome and introduction
50 years of Rapamycin discovery
10:45 – Svetlana Dokudovskaya - From Rapa Nui to Rapamycin
mTOR AND METABOLISM
11:00 – Michael Hall - mTOR signaling in growth, metabolism and disease
11:30 – Wilhelm Palm - mTORC1 controls endo-lysosomal nutrient acquisition
12:00 – Fried Zwartkruis - mTORC1 controls amino acid homeostasis via glutamine metabolism
12:15 – Nesli Ece Sen Arsovic - TORC2 is acutely regulated by glucose availability
12:30 – Nicolas Dupont - Role of mTOR and autophagy in mechanotransduction to control renal cell homeostasis
13:00 – Lunch
MOLECULAR MECHANISMS OF mTOR REGULATION
14:15 – Constantinos Demetriades - Spatial Separation of Nutrient Signaling to mTORC1
15:00 – Riko Hatakeyama - Spatially and functionally distinct TORC1 pools in yeast and beyond: Concept, approach, and implications
15:15 – Wim Annaert - VPS13C interaction with GATOR2 is required for mTORC1 activation in plasma membrane-endoplasmic reticulum contact sites
15:30 – Stephanie Fernandes - The tumor suppressor CYLD acts as a deubiquitinase for mTOR to constrain its activity
15:45 – Bernadette Carroll - mTORC1 signalling in cellular senescence and ageing
16:15 – Coffee Break
16:45 – David Sabatini - Nutrient sensing by the mTORC1 pathway
17:15 – Matthias Gehringer - Discovery of Highly Potent and Selective S6K2 Inhibitors
17:45 – Flash Talks students - Shiwani Kumari, Alessia Perciavalle, Vonda Koka, Jiyoung Pan, Samuel Laurent, Giorgia Piccoli, Ann-Sofie De Meulemeester
18:30 – Poster session
Friday - October 10th
NEUROBIOLOGY AND BRAIN DISORDERS
09:30 – Clémence Blouet - Dietary protein and appetite control: is it all about mTOR?
10:15 – Andrea Ballabio - mTORC1 substrate-specificity in cancer
10:45 – Mike Fainzilber - Stretching to Grow - Locally Translated mTOR Controls Interstitial Axonal Elongation
11:00 – Coffee Break
11:30 – Mauro Costa-Mattioli - Dissecting the role of mTOR complexes in epilepsy
12:15 – Paul Dutchak - ASO Therapeutics Targeting mTORC1-dependent Epilespy
12:30 – Joseph Bateman - Phosphoproteomics identifies RNA-metabolism defects in the brain in TSC
12:45 – Flash talks PIs - Dorota Ciołczyk-Wierzbicka, Julian Martinez-Agosto, Jacek Jaworski, Andrea Oeckinghaus
13:00 – Lunch
TUBEROUS SCLEROSIS COMPLEX
14:15 – Lisa Henske - Novel Disease Mechanisms in Tuberous Sclerosis Complex
15:00 – Anna Jansen - Closing the Care Gap: Advancing Neuropsychiatric Research in Tuberous Sclerosis Complex Through Global Collaboration and Digital Innovation
15:30 – Floor Jansen - Challenges in identifying relevant subependymal lesions in children with tuberous sclerosis complex
15:45 – Justyna Zmorzynska - Rac1 contributions to TSC-associated Neuropsychiatric Disorders
16:00 – Salvatore Gagliotta - TFEB drives renal pathology in Tuberous Sclerosis Complex human kidney organoids
16:15 – Coffee Break
GROWTH & DISEASE
16:45 – Mojgan Djavaheri-Mergny - The antidepressants sertraline and indatraline induce TFEB activation and immunogenic cell death
17:15 – Viktor Korolchuk - Role of mTOR in cellular ageing phenotypes
17:45 – Flash Talks students - Shiwani Kumari, Alessia Perciavalle, Vonda Koka, Jiyoung Pan, Samuel Laurent, Giorgia Piccoli, Ann-Sofie De Meulemeester
18:30 – Social event
Some Memories
2025 Partners
